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Definition and characteristics

Definition_and_characteristics

Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten in genetically susceptible individuals1. This disease causes atrophy of the villi lining the small intestine, which interferes with the absorption of nutrients such as proteins, fats, carbohydrates, minerals and vitamins. The prevalence of CD in the general population is estimated to be approximately 1%, being more frequent in women and children2. However, it is even higher in high-risk groups, such as pediatric patients with type 1 diabetes, reaching up to 4.2% in this group3.