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  • iVYCHECK GIP Urine  is an immunochromatographic test designed to detect Gluten Immunogenic Peptides (GIP) in urine samples. Firstly, gluten must be extracted from the sample, which is one of the most critical steps. Once extracted, detection is performed. In this step, the sample reacts with the conjugate antibodies (monoclonal antibodies A1 and G12) that are previously fixed in the strip. Then, the complex moves along the strip by capillary action. A red line appears in the result window on the strip to indicate a positive result. A negative result will be indicated by no line. A control protein is also present that will bind to immobilized antibodies. A green line will appear so as to indicate correct test performance.

  • The iVYCHECK GIP Urine kit from the iVYDAL In Vitro Diagnostics® line is a rapid immunochromatographic test that detects GIP in urine samples.

    This kit is especially indicated for:

    • Controlling gluten-free diet in celiac patients, patients with gluten-sensitivity or a gluten allergy.
    • Helping to correctly diagnose refractory celiac disease.
    • Controlling gluten-free diet for gluten-related disorders including eosinophilic esophagitis, lymphocytic duodenosis, iron deficiency anemia or type 1 diabetes, among other pathologies.
  • Sensitivity

    The limit of detection of the immunochromatographic test is 2.2 ng GIP/ml of urine sample.

    As the dynamic of GIP excretion varies between subjects, the amount of gluten ingested that can be detected can also vary. The single ingestion of 50mg of gluten has been detected, which is the daily dose considered to be harmful in celiac patients. A single ingestion of 500 mg of gluten is detectable in more than 85% of the cases in the following 2-24 hours.


    The test is capable of specifically detecting the presence of GIP from prolamins in wheat (gliadin), rye (secalin), barley (hordein) and, when present in high amounts, oat (avenins). No cross-reactivity is detected with naturally gluten-free foods that are considered safe for celiacs, such as rice, corn, buckwheat, soybean, millet, quinoa and amaranth. False positives have not been reported so far.

  • Kit REF. Formato
    iVYCHECK GIP Urine  KT-6412 10 test
    iVYCHECK GIP Urine  KT-6411 25 test