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iVYCHECK GIP Stool

  • iVYCHECK GIP Stool is an immunochromatographic test designed to detect GIP in stool samples. Firstly, gluten must be extracted from the sample, which is one of the most critical steps. Once extracted, detection is performed. In this step, the sample reacts with the conjugate antibodies (monoclonal antibodies A1 and G12) that are previously fixed in the strip. Then, the complex moves along the strip by capillary action. A RED line appears in the result window on the strip to indicate a positive result. A negative result will be indicated by no line. A control protein is also present that will bind to immobilized antibodies.A green line will appear so as to indicate correct test performance.

    ivycheck intended use

  • The iVYCHECK GIP Stool kit from the iVYDAL In Vitro Diagnostics® line is a rapid immunochromatographic test that detects GIP in stool samples.

    This kit is especially indicated for:

    • Controlling GFD in CD patients, patients with gluten-sensitivity or a gluten allergy.
    • Helping to correctly diagnose RCD.
    • Controlling GFD for gluten-related disorders including eosinophilic esophagitis, lymphocytic duodenosis, iron deficiency anemia or type 1 diabetes, among other pathologies.

    iVYCHECK use

  • Sensitivity

    The limit of detection of the immunochromatographic test 0.15 µg GIP/g of faecal sample. Compared to the iVYLISA GIP Stool test, the iVYCHECK GIP Stool test has a specificity of 99%.

    Specificity

    The test is capable of detecting specifically the presence of the toxic fraction for celiac patients of prolamins from wheat (gliadin), rye (secalin), barley (hordein) and and sufficiently high amounts of oat (avenins). However, no positive signal is observed when individuals consume rice, corn, buckwheat, soybean, millet, quinoa and amaranth, so the test has no interference with these ingredients free of gluten and thus safe for celiacs.

    Compared to the iVYLISA GIP Stool test, the iVYCHECK GIP Stool test has a specificity of 96%. However, it is possible that the iVYCHECK GIP Stool test can detect some positive samples not detected by the iVYLISA GIP Stool test due to the different antibody configuration and the heterogeneity of stool samples.

  • Kit REF. Format
    iVYCHECK GIP-Stool KT-5737 25 tests
    iVYCHECK GIP-Stool KT-6410 10 tests