iVYLISA GIP Stool is a quantitative Sandwich ELISA designed to detect and quantify GIP (mainly those equivalent to the 33-mer peptide) in stool samples. The capturing and detecting antibody is the G12, which is designed against the 33-mer peptide and which recognizes it and other equivalent immunotoxic peptides18.
The iVYLISA GIP Stool kit from the iVYDAL In Vitro Diagnostics® line is a sandwich ELISA assay that detects and quantifies GIP in stool samples. This kit is especially indicated for:
- Control of a gluten-free diet for celiac disease patients, patients with gluten-sensitivity or a gluten allergy.
- Diagnosis of refractory celiac disease and difficult diagnosis cases of celiac disease when a clinical supervision of the diet is required.
- Control of a gluten-free diet in gluten related disorders that could include eosinophilic esophagitis, lymphocytic duodenosis, iron deficiency anemia or type 1 diabetes, among other pathologies.
Diagnostic sensitivity was calculated from the data from the performance evaluation study, Deliac-01-2012, in which 68 healthy subjects (i.e. they did not have gastrointestinal diseases) were analyzed. The gluten consumption of all patients was checked by means of dietary questionnaires.
Diagnostic sensitivity: 98.5%
After analyzing hundreds of food matrices, cross-reactivity has yet to be described. Diagnostic specificity was calculated by taking samples from 12 under one-year-old subjects who were exclusively formula-fed (thus ensuring a strict GFD). The samples were analyzed, obtaining negative results in all cases.
Diagnostic specificity: 100%.
Kit REF. Format iVYLISA GIP Stool KT-5739 96 wells